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Proteintech
GSPT1 Polyclonal Antibody
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Product Details
10763-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GSPT1 Fusion Protein Ag1184 (265-633 aa encoded by BC009503)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QEERDKGKT VEVGRAYFET EKKHFTILDA PGHKSFVPNM IGGASQADLA VLVISARKGE FETGFEKGGQ TREHAMLAKT AGVKHLIVLI NKMDDPTVNW SNERYEECKE KLVPFLKKVG FNPKKDIHFM PCSGLTGANL KEQSDFCPWY IGLPFIPYLD NLPNFNRSVD GPIRLPIVDK YKDMGTVVLG KLESGSICKG QQLVMMPNKH NVEVLGILSD DVETDTVAPG ENLKIRLKGI EEEEILPGFI LCDPNNLCHS GRTFDAQIVI IEHKSIICPG YNAVLHIHTC IEEVEITALI CLVDKKSGEK SKTRPRFVKQ DQVCIARLRT AGTICLETFK DFPQMGRFTL RDEGKTIAIG KVLKLVPEKD (265-633 aa encoded by BC009503)
Target Information
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: eRF3a; Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; eukaryotic polypeptide chain release factor 3; eukaryotic release factor 3a; G1 to phase transition 1; G1 to S phase transition protein 1; G1 to S phase transition protein 1 homolog; G1-to-S phase transition 1; G1-to-S transition GTP binding protein; guanine nucleotide regulatory protein; unnamed protein product
Gene Aliases: 551G9.2; AI314175; AI326449; AV307676; C79774; ERF3A; ETF3A; G1st; GSPT1; Gst-1; GST1
UniProt ID: (Human) P15170, (Mouse) Q8R050
Entrez Gene ID: (Human) 2935, (Rat) 24420, (Mouse) 14852
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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