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Proteintech
GTF2A1 Polyclonal Antibody
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Product Details
21381-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GTF2A1 Fusion Protein Ag15994 (1-330 aa encoded by BC107156)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MANSANTNT VPKLYRSVIE DVINDVRDIF LDDGVDEQVL MELKTLWENK LMQSRAVDGF HSEEQQLLLQ VQQQHQPQQQ QHHHHHHHQQ AQPQQTVPQQ AQTQQVLIPA SQQATAPQVI VPDSKLIQHM NASNMSAAAT AATLALPAGV TPVQQILTNS GQLLQVVRAA NGAQYIFQPQ QSVVLQQQVI PQMQPGGVQA PVIQQVLAPL PGGISPQTGV IIQPQQILFT GNKTQVIPTT VAAPTPAQAQ ITATGQQQPQ AQPAQTQAPL VLQVDGTGDT SSEEDEDEEE DYDDDEEEDK EKDGAEDGQV EEEPLNSEDD VSDEEGQELF D (1-330 aa encoded by BC107156)
Target Information
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A) and several general initiation factors. One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: general transcription factor 2a, 1; general transcription factor IIA 1; General transcription factor IIA subunit 1; general transcription factor IIa, 1 (37kD and 19kD subunits); general transcription factor IIA, 1, 19/37kDa; glucose regulated protein, 58kD pseudogene; TFIIA alpha/beta; TFIIA alpha/beta subunits; TFIIA large subunit; TFIIA-42; TFIIAL; Transcription initiation factor IIA subunit 1; Transcription initiation factor TFIIA 42 kDa subunit
Gene Aliases: 6330549H03Rik; AA536742; AA959775; AW060250; GTF2A1; Tf2a; TF2A1; TFIIA; TFIIA-42; Tfiia1; TfIIAa/b; TFIIAL
UniProt ID: (Human) P52655, (Mouse) Q99PM3, (Rat) O08949
Entrez Gene ID: (Human) 2957, (Mouse) 83602, (Rat) 83830
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II general transcription initiation factor binding
DNA binding
protein binding
obsolete general RNA polymerase II transcription factor activity
TBP-class protein binding
protein heterodimerization activity
RNA polymerase II sequence-specific DNA binding transcription factor binding
RNA polymerase II repressing transcription factor binding
transcription coactivator activity
transcription factor binding
molecular_function
general transcription factor
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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