Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: VGYLIAGMK DVTEAQIGDT LCLHKQPVEP LPGFKSAKPM VFAGMYPLDQ SEYNNLKSAI EKLTLNDSSV TVHRDSSLAL GAGWRLGFLG LLHMEVFNQR LEQEYNASVI LTTPTVPYKA VLSSSKLIKE HREKEITIIN PAQFPDKSKV TEYLEPVVLG TIITPDEYTG KIMMLCEARR AVQKNMIFID QNRVMLKYLF PLNEIVVDFY DSLKSLSSGY ASFDYEDAGY QTAELVKMDI LLNGNTVEEL VTVVHKDKAH SIGKAICERL KDSLPRQLFE IAIQAAIGSK IIARETVKAY RKNVLAKCYG GDITRKMKLL KRQAEGKKKL RKIGNVEVPK DAFIKVLKTQ SSK (318-669 aa encoded by BC036768)
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EF-4; Elongation factor 4 homolog; GTP-binding protein GUF1 homolog; GTPase GUF1; GTPase of unknown function 1; GUF1 GTPase homolog; Ribosomal back-translocase; Translation factor GUF1, mitochondrial
Gene Aliases: 4631409J12; AA407526; EF-4; GUF1
UniProt ID: (Human) Q8N442, (Mouse) Q8C3X4
Entrez Gene ID: (Human) 60558, (Mouse) 231279
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