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|Tested species reactivity||Bovine, Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Synthetic peptide corresponding to the amino acids 729 - 742 of the native molecule conjugated to KLH, Peptide sequence: FVGWFLGWDDDYWS|
|Storage buffer||PBS, pH 7.2|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Predicted to react with mouse and pig based on sequence homology.
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin which appears to account for the difference in relative molecular weights.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
actin-depolymerizing factor; ADF; brevin; gelsolin; gelsolin (amyloidosis, Finnish type); MGC28083; RP23-186B18.2
ADF; AGEL; GSN