This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-27350 targets Gelsolin in IF, IHC (P), and WB applications and shows reactivity with Human, rat, and mouse samples.
The PA5-27350 immunogen is recombinant fragment corresponding to a region within amino acids 561 and 782 of Human Gelsolin.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-depolymerizing factor; ADF; AGEL; Brevin; Gelsolin
Gene Aliases: ADF; AGEL; Gsb; GSN