This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: H1299, HeLa, human plasma, rat plasma, mouse plasma.
Predicted reactivity: Mouse (94%), Rat (94%), Chicken (81%), Sheep (98%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-depolymerizing factor; ADF; ADFBrevin; AGEL; Brevin; DKFZp313L0718; Gelsolin; RP11-477J21.1
Gene Aliases: ADF; AGEL; Gsb; GSN
Molecular Function: non-motor actin binding protein