PA1-9597 detects Obestatin in human, mouse and rat samples.
PA1-9597 has been successfully used in ELISA procedures.
PA1-9597 immunogen mouse obestatin peptide (FNAPFDVGIKLSGAQYQQHGRAL), aa 76-98 of Ghrelin precursor.
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Appetite-regulating hormone; Ghrelin; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; MTLRP; Obestatin; Obestatin-13; Obestatin-23; preproghrelin; proghrelin; Protein M46
Gene Aliases: 2210006E23Rik; Ghr; Ghrl; m46; MTLRP; MTLRPAP