|Tested species reactivity||Rat|
|Published species reactivity||Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal region of rat GRIA2/3 conjugated to KLH|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
This antibody is predicted to react with chicken, human, mouse and zebrafish based on 100% sequence homology.
This antibody is specific for the ~100 kDa GluR2/3 protein.
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AMPA and GABA(A/B) receptor subunit expression in the cortex of adult squirrel monkeys during peripheral nerve regeneration.
PA1-4660 was used in immunohistochemistry to study the immunohistochemical expression of AMPA and GABAA/B subunits in adult squirrel monkey cortex during regeneration of peripheral nerve damage
|Mowery TM,Walls SM,Garraghty PE||Brain research (1520:80)||2013|