PA1-28366 detects Glucocorticoid receptor from non-human primate, human samples.
PA1-28366 has been successfully used in Western blot applications.
The PA1-28366 immunogen is: Peptide consisting of amino acids 150-175 of squirrel monkey glucocorticoid receptor coupled to diptheria toxoid. This sequence is identical in human glucocorticoid receptor except for 2 amino acids (lowercase) :N terminus - AP
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the
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Protein Aliases: GCCR; GCR; glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor; Glucocorticoid receptor lymphocyte; GR; GRL; Grl1; NR3C1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene Aliases: GCCR; GCR; GCRST; GR; GRL; NR3C1
UniProt ID: (Human) F5ATB7
Entrez Gene ID: (Human) 2908