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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
ELISA (ELISA) |
1:10,000 | - |
Immunoprecipitation (IP) |
1:50-1:250 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide taken within amino acid reigon 850-950. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5-1.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AI853806; AMPA 1; AMPA-selective glutamate receptor 1; GluA1; GLUH 1; GluR K1; GluR-1; GluR-A; GluR-K1; GluRK1; glutamate receptor; Glutamate receptor 1; Glutamate receptor ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA 1; GPRC1A; Gria 1; GRM1A; HGBR1; HIPA; MGC13325; MGC133252; NMDA1; NMDAR1; OTTHUMP00000160643; OTTHUMP00000165781; OTTHUMP00000224241; OTTHUMP00000224242; OTTHUMP00000224243; RP11-350O14.1
Gene Aliases: GluA1; GLUH1; GLUR1; GLURA; GRIA1; HBGR1
UniProt ID: (Human) P42261
Entrez Gene ID: (Human) 2890
Molecular Function:
transmembrane signal receptor
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