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FIGURE: 1 / 1
GlyT1 Antibody (PA5-116669) in WB
Western blot analysis of GlyT1 in various lysates. Samples were incubated with GlyT1 Polyclonal antibody (Product # PA5-116669) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-116669
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_9640122)
Conjugate
Form
Liquid
Concentration
1.58 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901300
Product Specific Information
Positive Samples: SH-SY5Y, K562, MCF7, mouse liver, C6, rat liver
Immunogen sequence: MSGGDTRAAI ARPRMAAAHG PVAPSSPEQV TLLPVQRSFF LPPFSGATPS TSLAESVLKV WHGAYNSGLL PQLMAQHSLA MAQNGAVPSE ATKRDQNLKR GNWGNQIEFV
Target Information
Slc6a9 is a glycine transporter (GlyTs) that belong to a family of high affinity Na+- and Cl-dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 (Slc6a9) and GlyT2. Slc6a9 are predominantly located on glia within caudal brain areas. The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by the Slc6a9 gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Infantile Glycine Encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycine transporter 1; glycine transporter variant 1a; GlyT-1; Sodium- and chloride-dependent glycine transporter 1; solute carrier family 6 (neurotransmitter transporter, glycine), member 9; Solute carrier family 6 member 9
Gene Aliases: GLYT-1; GLYT-1b; GLYT1; SLC6A9
UniProt ID: (Human) P48067, (Mouse) P28571, (Rat) P28572
Entrez Gene ID: (Human) 6536, (Mouse) 14664, (Rat) 116509
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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