The product of this gene belongs to the FGGY kinase family of proteins and encodes glycerol kinase. Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Defects in this gene are the cause of glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ASTP; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; ATP:glycerol 3-phosphotransferase; EC 220.127.116.11; GK; GK 3; GK3P; GKl; GKP3; GKTB; glycerokinase; Glycerokinase 3; Glycerol kinase; Glycerolkinase
Gene Aliases: ASTP; D930012N15Rik; GK; GK1; GKD; Gyk
Molecular Function: carbohydrate kinase