The product of this gene belongs to the FGGY kinase family of proteins and encodes glycerol kinase. Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Defects in this gene are the cause of glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: ASTP; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; ATP:glycerol 3-phosphotransferase; EC 220.127.116.11; GK; GK 3; GK3P; GKl; GKP3; GKTB; glycerokinase; Glycerokinase 3; Glycerol kinase; Glycerolkinase
Gene Aliases: ASTP; D930012N15Rik; GK; GK1; GKD; Gyk