Immunogen sequence: MEQALTGEAQ SRWPRRGGSG AMAEAPGPSG ESRGHSATQL PAEKTVGGPS RGCSSSVLRV SQLVLQAIST HKGLTLAALK KELGNAGYEV RRKS
Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 48%.
Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H1 histone family, member N, testis-specific; H1FNT; H1T2, HANP1; HANP1; Haploid germ cell-specific nuclear protein 1; Histone H1t2; testis secretory sperm-binding protein Li 223n; Testis-specific H1 histone
Gene Aliases: H1.7; H1FNT; H1T2; HANP1
UniProt ID: (Human) Q75WM6
Entrez Gene ID: (Human) 341567