Immunogen sequence: ATQCFQLSNM FNPQTEEEVG WDTEIKDDVI EECNKHGGVI HIYVDKNSAQ GNVYVKCPSI AAAIAAVNAL HGRWFAGKMI TAAYVPLPTY HNLFPDSMTA TQLLVPSRR; Positive Samples: BxPC-3, U-251MG, 293T, LO2, Mouse brain, Mouse heart; Cellular Location: Nucleus speckle
The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.
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Protein Aliases: CAPER alpha; Coactivator of activating protein 1 and estrogen receptors; coactivator of activating protein-1 and estrogen receptors; Coactivator of AP-1 and ERs; functional spliceosome-associated protein 59; Hepatocellular carcinoma protein 1; RNA-binding motif protein 39; RNA-binding protein 39; RNA-binding region (RNP1, RRM) containing 2; RNA-binding region-containing 2; RNA-binding region-containing protein 2; Splicing factor HCC1; Transcription coactivator CAPER
Gene Aliases: 1500012C14Rik; 2310040E03Rik; B330012G18Rik; C79248; CAPER; CAPERalpha; FSAP59; HCC1; R75070; RBM39; Rnp1; RNPC2; Rrm