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Bioss
HCN3 Polyclonal Antibody
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Product Details
BS-9856R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HCN3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HAC-3; hyperpolarization activated cyclic nucleotide-gated potassium channel 3; Hyperpolarization-activated cation channel 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; MGC131493; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
Gene Aliases: BCNG-4; Bcng4; Hac3; HCN3; Hcn4; KIAA1535
UniProt ID: (Human) Q9P1Z3, (Mouse) O88705, (Rat) Q9JKA8
Entrez Gene ID: (Human) 57657, (Mouse) 15168, (Rat) 114245
voltage-gated sodium channel activity
voltage-gated potassium channel activity
cAMP binding
nucleotide binding
ion channel activity
intracellular cAMP activated cation channel activity
voltage-gated ion channel activity
potassium channel activity
sodium channel activity
protein binding
ion channel
transporter
kinase
regulation of ion transmembrane transport
sodium ion transmembrane transport
regulation of membrane potential
regulation of postsynaptic membrane potential
cellular response to cAMP
potassium ion transmembrane transport
response to cisplatin
cellular response to dopamine
transport
ion transport
potassium ion transport
sodium ion transport
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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