Search Thermo Fisher Scientific
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Immunogen sequence: SNIYQENFS EYQEIAVQNH SSETCQHVSE PEDLSPKMYQ EISVLQDNSS KICQDMKEPE DNSPNTCQVI SVIQDHPFKM YQDMAKREDL APKMCQEAAV PKILPCPTSE DTADLAGCSL QAYPKPDVPK GYILDTDQNP AEPEEYNETD QGIAETEGLF PKIQEIAEPK DLSTKTHQES AEPKYLPHKT CNEIIVPKAP SHKTIQETPH SEDYSIEINQ ETPGSEKYSP ETYQEIPGLE EYSPEIYQET SQLEEYSPEI YQETPGPEDL STETYKNKDV PKECFPEPHQ ETGGPQGQDP KAHQEDAKDA YTFPQEMKEK PKEEPGIPAI LNESHPENDV YSYVLF (139-483 aa encoded by BC048324)
HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression of HEMGN block the TPA-induced megakaryocytic differentiation in the K562 cell model. HEMGN may also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EDAG-1; Erythroid differentiation-associated gene protein; Hemogen; Hemopoietic gene protein; mNDR; Negative differentiation regulator protein; nuclear protein
Gene Aliases: 4921524M03Rik; AI317176; CT155; EDAG; EDAG-1; HEMGN; Hgn; mNDR; NDR; PRO1037; PRO1620
UniProt ID: (Human) Q9BXL5, (Mouse) Q9ERZ0
Entrez Gene ID: (Human) 55363, (Mouse) 93966
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