Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: WTVNEALIQK WLSYPSGRFP VEIANEIDGT FSSSGCLNGS FLAVSNDDHY RTGTRFSGVD MNAARLLFHK LIQPDHPQIS QQVAASLEKN LIPKLTSSLP DVEALRFYLT LPECPLMSDS NNFTTIAIPF GTALVNLEKA PLKVLENWWS VLEPPLFLKI VELFKEVVVH LLKLYKIGIP PSERRIFNSF LHTALKVLEI LHRVNEKMGQ IIQYDKFYIH EVQELIDIRN DYINWVQQQA YGMLADIPVT ICTYPFVFDA QAKTTLLQTD AVLQMQMAID QAHRQNVSSL FLPVIESVNP C
Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HECT domain and RCC1-like domain-containing protein 4; hect domain and RLD 4; HECT-type E3 ubiquitin transferase HERC4; Probable E3 ubiquitin-protein ligase HERC4
Gene Aliases: 1700056O17Rik; 4921531D01Rik; 9530080M15Rik; HERC4; KIAA1593; mKIAA1593
UniProt ID: (Human) Q5GLZ8, (Mouse) Q3UPX2, (Rat) Q5PQN1
Entrez Gene ID: (Human) 26091, (Mouse) 67345, (Rat) 309758
Molecular Function: ubiquitin-protein ligase
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