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Immunogen sequence: MMATPNQTA CNAESPVALE EAKTSGAPGS PQTPPERHDS GGSLPLTPRM ESHSEDEDLA GAVGGLGWNS RSPRTQSPGG CSAEAVLARK KHRRRPSKRK RHWRPYLELS WAEKQQRDER QSQRASRVRE EMFAKGQPVA PYNTTQFLMN DRDPEEPNLD VPHGISHPGS SGESEAGDSD GRGRAHGEFQ RKDFSETYER FHTESLQGRS KQELVRDYLE LEKRLSQAEE ETRRLQQLQA CTGQQSCRQV EELAAEVQRL RTENQRLRQE NQMWNREGCR CDEEPGT (1-286 aa encoded by BC025970)
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hexamethylene bis-acetamide inducible 2; Hexamethylene bis-acetamide-inducible protein 2; hexamethylene-bis-acetamide-inducible transcript 2; hexamthylene bis-acetamide inducible 2; MAQ1 paralog; Protein HEXIM2
Gene Aliases: 4933402L21Rik; HEXIM2; L3; RGD1311635
UniProt ID: (Human) Q96MH2, (Mouse) Q9D4C7
Entrez Gene ID: (Human) 124790, (Rat) 303580, (Mouse) 71059
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