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Immunogen sequence: IIGGSSSLPG SHPWLAAIYI GDSFCAGSLV HTCWVVSAAH CFSHSPPRDS VSVVLGQHFF NRTTDVTQTF GIEKYIPYTL YSVFNPSDHD LVLIRLKKKG DRCATRSQFV QPICLPEPGS TFPAGHKCQI AGWGHLDENV SGYSSSLREA LVPLVADHKC SSPEVYGADI SPNMLCAGYF DCKSDACQGD SGGPLACEKN GVAYLYGIIS WGDGCGRLHK PGVYTRVANY VDWINDRIRP PRRLVAPS; Positive Samples: LO2, BT-474, SW620, Mouse liver, Mouse pancreas, Rat liver
This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants.
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Protein Aliases: Hepatocyte growth factor activator; HGF activator
Gene Aliases: HGFA; HGFAC
UniProt ID: (Human) Q04756, (Mouse) Q9R098
Entrez Gene ID: (Human) 3083, (Rat) 58947, (Mouse) 54426
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