The recommended shelf life for this product is 1 year from date of receipt.
Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 14-3-3-associated AKT substrate; fetal liver expressing gene 1; Fetal liver-expressing gene 1 protein; Holliday junction recognition protein; Up-regulated in lung cancer 9
Gene Aliases: FAKTS; FLEG1; hFLEG1; HJURP; URLC9
UniProt ID: (Human) Q8NCD3
Entrez Gene ID: (Human) 55355