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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human HK1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.97 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2804550 |
Immunogen sequence: KKIDKYLYAM RLSDETLIDI MTRFRKEMKN GLSRDFNPTA TVKMLPTFVR SIPDGSEKGD FIALDLGGSS FRILRVQVNH EKNQNVHMES EVYDTPENIV HGSGSQLFDH VAECLGDFME KRKIKDKKLP VGFTFSFPCQ QSKIDEAILI TWTKRFKASG VEGADVVKLL NKAIKKRGDY DANIVAVVND TVGTMMTCGY DDQHCEVGLI IGTGTNACYM EELRHIDLVE GDEGRMCINT EWGAFGDDGS LEDIRTEFDR EIDRGSLNPG KQLFEKMVSG M; Positive Samples: MCF7, 293T, Jurkat, THP-1, NIH/3T3, K-562, Mouse skeletal muscle, rat testis; Cellular Location: Mitochondrion outer membrane
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Brain form hexokinase; downeast anemia; glycolytic enzyme; hexokinase I; hexokinase IR; Hexokinase type I; Hexokinase, tumor isozyme; Hexokinase-1; Hexokinase-A; HK I
Gene Aliases: BB404130; dea; HEXOKIN; hexokinase; HK; Hk-1; HK1; Hk1-s; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; mHk1-s
UniProt ID: (Human) P19367, (Rat) P05708, (Mouse) P17710
Entrez Gene ID: (Human) 3098, (Rat) 25058, (Mouse) 15275
Molecular Function:
kinase
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