Immunogen sequence: LLQEMLLGGS PSDAPHAHHP LHPHLMQEHM GTNVIVANTM PTHLSNGQMC EWPRPRGQAA TPETPQPSPP GGSGSEPYKL LPGAVATIVK PLSAIPQPTI TKQEV
HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.
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Protein Aliases: hepatic nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; HNF4; HNF4alpha10/11/12; MODY; MODY1; NR2A1; Nuclear receptor subfamily 2 group A member 1; TCF-14; TCF14; Transcription factor 14; Transcription factor HNF-4
Gene Aliases: FRTS4; HNF4; HNF4A; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14
UniProt ID: (Human) Q99864
Entrez Gene ID: (Human) 3172