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Proteintech
HOMER3 Polyclonal Antibody
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Product Details
16624-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HOMER3 Fusion Protein Ag9923 (1-361 aa encoded by BC012113)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSTAREQPI FSTRAHVFQI DPATKRNWIP AGKHALTVSY FYDATRNVYR IISIGGAKAI INSTVTPNMT FTKTSQKFGQ WADSRANTVY GLGFASEQHL TQFAEKFQEV KEAARLAREK SQDGGELTSP ALGLASHQVP PSPLVSANGP GEEKLFRSQS ADAPGPTERE RLKKMLSEGS VGEVQWEAEF FALQDSNNKL AGALREANAA AAQWRQQLEA QRAEAERLRQ RVAELEAQAA SEVTPTGEKE GLGQGQSLEQ LEALVQTKDQ EIQTLKSQTG GPREALEAAE REETQQKVQD LETRNAELEH QLRAMERSLE EARAERERAR AEVGRAAQLL DVRLFELSEL REGLARLAEA AP (1-361 aa encoded by BC012113)
Target Information
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: homer homolog 3; Homer protein homolog 3; Homer, neuronal immediate early gene, 3; Homer-3; VASP/Ena-related gene up-regulated during seizure and LTP 3; Vesl-3
Gene Aliases: AW146114; HOMER-3; HOMER3; Vesl-3; VESL3
UniProt ID: (Human) Q9NSC5, (Mouse) Q99JP6, (Rat) Q9Z2X5
Entrez Gene ID: (Human) 9454, (Mouse) 26558, (Rat) 29548
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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