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Product Details
PA5-143086
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-SEQASAQSEPSP.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933725
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box 1C; homeo box A5; Homeobox protein Hox-1C; Homeobox protein Hox-A5; homeobox protein HOXA5; Hox-1C
Gene Aliases: HOX1; HOX1.3; HOX1C; HOXA5
UniProt ID: (Human) Q96CY6
Entrez Gene ID: (Pig) 100499568, (Human) 3202
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
homeodomain transcription factor
respiratory system process
transcription from RNA polymerase II promoter
anterior/posterior pattern specification
positive regulation of receptor biosynthetic process
cell migration
negative regulation of angiogenesis
thyroid gland development
regulation of mammary gland epithelial cell proliferation
multicellular organism growth
positive regulation of apoptotic process
positive regulation of myeloid cell differentiation
negative regulation of erythrocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
lung alveolus development
embryonic skeletal system morphogenesis
bronchiole development
epithelial tube branching involved in lung morphogenesis
lung goblet cell differentiation
lung-associated mesenchyme development
trachea cartilage morphogenesis
intestinal epithelial cell maturation
mesenchymal-epithelial cell signaling
mammary gland epithelial cell differentiation
mammary gland alveolus development
cell-cell signaling involved in mammary gland development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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