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Product Details
PA5-103892
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human HOXC10(Accession Q9NYD6), corresponding to amino acid residues D169-E188. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2853224 |
Target Information
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box C10; Homeobox protein Hox-3.6; Homeobox protein Hox-3I; Homeobox protein Hox-C10; homeoprotein C10
Gene Aliases: AI506621; Hox-3.6; HOX3I; Hoxc-10; HOXC10
UniProt ID: (Human) Q9NYD6, (Mouse) P31257
Entrez Gene ID: (Human) 3226, (Mouse) 209448
Molecular Function:
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
skeletal system development
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
anterior/posterior pattern specification
proximal/distal pattern formation
spinal cord motor neuron cell fate specification
embryonic limb morphogenesis
neuromuscular process
multicellular organism development
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