Recommended positive controls: HeLa, HepG2, mouse muscle.
Predicted reactivity: Mouse (97%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.
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Protein Aliases: homeo box C10; Homeobox protein Hox-3.6; Homeobox protein Hox-3I; Homeobox protein Hox-C10; homeoprotein C10; Hox3.5 homeobox
Gene Aliases: AI506621; Hox-3.6; HOX3I; Hoxc-10; HOXC10