Predicted to react with Mouse samples.
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: d10; homeo box 4D; homeo box D10; Homeobox protein Hox-4.5; Homeobox protein Hox-4D; Homeobox protein Hox-4E; Homeobox protein Hox-5.3; Homeobox protein Hox-D10; Hox-45
Gene Aliases: AI385591; AI874987; Hox-4.4; Hox-4.5; Hox-5.3; HOX4; HOX4D; HOX4E; Hoxd-10; HOXD10
Molecular Function: homeodomain transcription factor