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Product Details
PA5-67561
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human HOXD3.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2688463
Product Specific Information
Predicted to react with Mouse samples.
Target Information
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box D3; homeo box D4; Homeobox protein Hox-4.1; Homeobox protein Hox-4A; Homeobox protein Hox-D3; Homeobox protein MH-19; Hox-4.1, mouse, homolog of; MGC10470
Gene Aliases: Hox-4.1; Hox-5.5; HOX1D; HOX4; HOX4A; Hoxd-3; HOXD3
UniProt ID: (Human) P31249, (Mouse) P09027
Entrez Gene ID: (Human) 3232, (Mouse) 15434
transcription, DNA-templated
regulation of transcription, DNA-templated
cell-matrix adhesion
Notch signaling pathway
anterior/posterior pattern specification
positive regulation of gene expression
glossopharyngeal nerve morphogenesis
thyroid gland development
positive regulation of neuron differentiation
embryonic skeletal system morphogenesis
cartilage development
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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