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PGDS is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 2.5.1.18; EC 5.3.99.2; Glutathione S-transferase; glutathione S-transferase sigma; Glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; Glutathione-requiring prostaglandin D synthase; GST class-sigma; H-PGDS; Hematopoietic prostaglandin D synthase; hematopoietic prostaglandin D2 synthase; Prostaglandin-H2 D-isomerase
Gene Aliases: GSTS; GSTS1; GSTS1-1; HPGDS; PGD2; PGDS; PTGDS2
UniProt ID: (Human) O60760
Entrez Gene ID: (Human) 27306
Molecular Function:
transferase
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