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|Tested species reactivity||Human, Primate, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide corresponding to human Corticosteroid 11-beta-dehydrogenase isozyme 2.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-27918 detects HSD11B2 from human, rat, and chimpanzee samples.
PA1-27918 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27814 immunogen is a synthetic peptide corresponding to human Corticosteroid 11-beta-dehydrogenase isozyme 2.
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels. thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
-HSD11 type II; 11-beta-HSD type II; 11-beta-HSD2; 11-beta-hydroxysteroid dehydrogenase type 2; 11-beta-hydroxysteroid dehydrogenase type II; 11-DH2; 11-HSD type II; AME; AME1; corticosteroid 11-beta-dehydrogenase isozyme 2; HSD11K; HSD2; hydroxysteroid (11-beta) dehydrogenase 2; Hydroxysteroid dehydrogenase, 11 beta type 2; NAD-dependent 11-beta-hydroxysteroid dehydrogenase; SDR9C3; short chain dehydrogenase/reductase family 9C member 3
AME; AME1; HSD11B2; HSD11K; HSD2; SDR9C3