This target displays homology in the following species: Cow: 79%; Dog: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rabbit: 100%; Rat: 100%
The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.
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Protein Aliases: 17-beta-HSD 12; 17-beta-hydroxysteroid dehydrogenase 12; 17beta-HSD type 12; 3-ketoacyl-CoA reductase; Estradiol 17-beta-dehydrogenase 12; hydroxysteroid (17-beta) dehydrogenase 12; KAR; keratoadhesin; keratonectin; KIK-I; Short chain dehydrogenase/reductase family 12C member 1; short chain dehydrogenase/reductase family 12C, member 1; smooth muscle-specific 17 beta-hydroxysteroid dehydrogenase type 3; steroid dehydrogenase; steroid dehydrogenase homolog; Very-long-chain 3-oxoacyl-CoA reductase
Gene Aliases: 2610510O05Rik; AI172963; BOS_15148; HSD17B12; KAR; KIK-I; Kik1; SDR12C1