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Invitrogen
HSD17B3 Polyclonal Antibody
FIGURE: 1 / 7
HSD17B3 Antibody (PA5-30063) in ICC/IF
HSD17B3 Polyclonal Antibody detects HSD17B3 protein at cytoplasm by confocal immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: HSD17B3 protein stained by HSD17B3 Polyclonal Antibody (Product # PA5-30063) diluted at 1:500. Blue: Hoechst 33342 staining. [Images captured by Olympus FV10i Confocal Laser Scanning Microscope].
Product Details
PA5-30063
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 122 and 310 of Human HSD17B3
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547537
Product Specific Information
Recommended positive controls: Raji.
Predicted reactivity: Pig (81%), Rhesus Monkey (97%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 17(beta)HSD type 3; 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; 17beta-HSD; estradiol 17 beta-dehydrogenase 3; Estradiol 17-beta-dehydrogenase 2; hydroxysteroid (17-beta) dehydrogenase 3; hydroxysteroid dehydrogenase 3; Short chain dehydrogenase/reductase family 12C member 2; short chain dehydrogenase/reductase family 12C, member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
Gene Aliases: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058, (Mouse) P70385, (Rat) O54939
Entrez Gene ID: (Human) 3293, (Mouse) 15487, (Rat) 117182
lipid metabolic process
steroid biosynthetic process
metabolic process
oxidation-reduction process
organic acid metabolic process
response to herbicide
response to metal ion
response to lead ion
response to organic cyclic compound
response to activity
response to insecticide
insecticide metabolic process
biphenyl metabolic process
phenol-containing compound metabolic process
hippocampus development
response to nutrient levels
cellular response to hormone stimulus
response to vitamin E
Leydig cell differentiation
response to L-ascorbic acid
response to estrogen
response to ethanol
response to arsenic-containing substance
response to cadmium ion
response to steroid hormone
response to corticosterone
response to fungicide
testosterone biosynthetic process
response to fatty acid
cellular response to antibiotic
cellular response to gonadotropin stimulus
androgen biosynthetic process
male genitalia development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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