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Product Details
PA5-65521
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human HSF4. Recombinant protein control fragment (Product #RP-104858).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2665144
Product Specific Information
Immunogen sequence: GKGSFSPEGPR NAQQPEPGDP REIPDRGPLG LESGDRSPES LLPPMLLQPP QESVEPAGPL DVLGPSLQGR EWTLMDLDME LSLMQPLVPE RGEPELAVKG LNSPSP
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 74%.
Target Information
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AT-HSFB1; ATHSF4; cataract; Heat shock factor protein 4; Heat shock transcription factor 4; hHSF4; HSF 4; HSFB1; HSTF 4; Marner
Gene Aliases: CTM; CTRCT5; HSF4
UniProt ID: (Human) Q9ULV5
Entrez Gene ID: (Human) 3299
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
visual perception
positive regulation of cell proliferation
histone H3-K9 demethylation
camera-type eye development
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cell development
protein homotrimerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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