Peptide sequence: SWDENGTCIV INEELFKKEI LETKAPYRIF QTDAIKSFVR QLNLYGFSKI
Sequence homology: Cow: 79%; Dog: 79%; Human: 100%; Mouse: 79%; Rat: 79%
This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Protein Aliases: Heat shock transcription factor 2-like protein; Heat shock transcription factor, Y-linked; HSF2-like; HSF2L; HSFY; HSFY2; Y-linked 1
Gene Aliases: HSF2L; HSFY; HSFY1; HSFY2
UniProt ID: (Human) Q96LI6
Entrez Gene ID: (Human) 86614