PA5-28090 targets 5HT1A receptor in WB and IHC (P) applications and shows reactivity with Human, rat, and mouse samples.
The PA5-28090 immunogen is synthetic peptide corresponding to a region within amino acids 178 and 270 of Human 5HT1A receptor.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
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Protein Aliases: 5-HT-1A; 5-HT1A; 5-HT1A receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor 1A; 5HT1a; ADRB2RL1; ADRBRL1; G protein coupled receptor; G-21; G-protein coupled receptor 18; guanine nucleotide-binding regulatory protein-coupled receptor; Serotonin receptor 1A
Gene Aliases: 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; G-21; Gpcr18; HTR1A; PFMCD; RAT5HT1A