Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%) Marmoset, Bat (95%) Horse (90%).
Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
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Protein Aliases: 5-HT 2B receptor; 5-HT(2B); 5-HT-2B; 5-HT2B; 5-HT2b receptor; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; 5-hydroxytryptamine 2B receptor; 5-hydroxytryptamine receptor 2B; 5-hydroxytryptamine receptor 2B variant b; 5HT2B Receptor; HTR2B; Serotonin 2b receptor; Serotonin 5-HT-2b receptor; Serotonin receptor 2B
Gene Aliases: 5-HT(2B); 5-HT-2B; 5-HT2B; HTR2B
UniProt ID: (Human) P41595
Entrez Gene ID: (Human) 3357