The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1.
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Protein Aliases: Checkpoint protein HUS1; hHUS1; HUS1 checkpoint homolog; HUS1 protein; hus1+-like protein
Gene Aliases: hHUS1; HUS1
UniProt ID: (Human) O60921
Entrez Gene ID: (Human) 3364
Molecular Function: DNA metabolism protein