|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 194 of Human Histone H1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Contains||0.025% ProClin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30055 targets Histone H1 in IF, IHC (P), and WB applications and shows reactivity with Human, Rat, and Mouse samples.
The PA5-30055 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 194 of Human Histone H1.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H1 histone family, member 1; H1 VAR.3; H1(0); H1-0; H1.0; H10; H1a; H1FV; histone 1, H1a; histone H1'; histone H1(0); histone H1.0; Histone H1.1; Histone H1a
Gene Aliases: H1.1; H1A; H1F1; H1var3; HIST1; HIST1H1A
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