Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L58, mitochondrial; Digestion substraction 1; DS-1; Immature colon carcinoma transcript 1 protein; Immature colon carcinoma transcript 1 protein homolog; Mitochondrial large ribosomal subunit protein mL62; MRP-L58; Peptidyl-tRNA hydrolase ICT1, mitochondrial
Gene Aliases: 1110001A02Rik; 1110002E03Rik; DS-1; DS1; ICT1; MRP-L58; MRPL58