Recommended positive controls: A431, H1299, HeLa, HepG2, mouse brain, rat brain.
Predicted reactivity: Mouse (94%), Rat (95%), Zebrafish (90%), Dog (93%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Abeta-degrading protease; FLJ35968; Insulin degrading enzyme; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin
Gene Aliases: 1300012G03Rik; 4833415K22Rik; AA675336; AI507533; IDE; INSDEGM; INSULYSIN
Molecular Function: metalloprotease