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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • IDH3A Antibodies

          Proteintech

          IDH3A Polyclonal Antibody, CoraLite® Plus 488

          View all (10) IDH3A antibodies

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          Cite IDH3A Polyclonal Antibody, CoraLite® Plus 488

          • Antibody Testing Data (1)
          IDH3A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          IDH3A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          IDH3A Antibody (CL488-15909) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CoraLite® Plus 488 IDH3A antibody (CL488-15909) at dilution of 1:200, CL594-phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          IDH3A Antibody in Immunocytochemistry (ICC/IF)

          Product Details

          CL488-15909

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          IDH3A fusion protein Ag8662

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: MAGPAWISK VSRLLGAFHN PKQVTRGFTG GVQTVTLIPG DGIGPEISAA VMKIFDAAKA PIQWEERNVT AIQGPGGKWM IPSEAKESMD KNKMGLKGPL KTPIAAGHPS MNLLLRKTFD LYANVRPCVS IEGYKTPYTD VNIVTIRENT EGEYSGIEHV IVDGVVQSIK LITEGASKRI AEFAFEYARN NHRSNVTAVH KANIMRMSDG LFLQKCREVA ESCKDIKFNE MYLDTVCLNM VQDPSQFDVL VMPNLYGDIL SDLCAGLIGG LGVTPSGNIG ANGVAIFESV HGTAPDIAGK DMANPTALLL SAVMMLRHMG LFDHAARIEA ACFATIKDGK SLTKDLGGNA KCSDFTEEIC RRVKDLD

          Target Information

          Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: H-IDH alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase 3 (NAD+) alpha; Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH

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          Gene Aliases: 1110003P10Rik; 1500012E04Rik; AA407078; AI316514; IDH3A

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          UniProt ID: (Human) P50213, (Mouse) Q9D6R2, (Rat) Q99NA5

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          Entrez Gene ID: (Human) 3419, (Mouse) 67834, (Rat) 114096

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          Function(s)
          magnesium ion binding isocitrate dehydrogenase (NAD+) activity NAD binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding dehydrogenase
          Process(es)
          carbohydrate metabolic process tricarboxylic acid cycle isocitrate metabolic process 2-oxoglutarate metabolic process NADH metabolic process oxidation-reduction process
          It has to be done as per old AB suggested Products section.
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