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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 79 and 171 of Human IDO1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28066 targets IDO1 in WB applications and shows reactivity with Human samples.
The PA5-28066 immunogen is synthetic peptide corresponding to a region within amino acids 79 and 171 of Human IDO1.
Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 22.214.171.124). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
3 dioxygenase; 3-dioxygenase; IDO; IDO-1; INDO; indolamine 2; indolamine 2,3 dioxygenase; indole 2; indole 2,3-dioxygenase; indoleamine 2,3-dioxygenase 1; indoleamine-pyrrole 2; indoleamine-pyrrole 2,3-dioxygenase
IDO; IDO-1; INDO