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          • Primary Antibodies ›
          • Iduronate 2 Sulfatase Antibodies

          Proteintech

          IDS Polyclonal Antibody

          View all (14) Iduronate 2 Sulfatase antibodies

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          Cite IDS Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          IDS Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          IDS Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          IDS Antibody (29375-1-AP) in WB

          Various lysates were subjected to SDS PAGE followed by western blot with 29375-1-AP (IDS antibody) at dilution of 1:1,000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          IDS Antibody in Western Blot (WB)
          IDS Polyclonal Antibody

          Product Details

          29375-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          IDS fusion protein Ag31132
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.7 mg/mL

          Amount

          105 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: PSSEKYENTK TCRGPDGELH ANLLCPVDVL DVPEGTLPDK QSTEQAIQLL EKMKTSASPF FLAVGYHKPH IPFRYPKEFQ KLYPLENITL APDPEVPDGL PPVAYNPWMD IRQREDVQAL NISVPYGPIP VDFQEDQSST GFRLKTSSTR KYK

          Target Information

          Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Alpha-L-iduronate sulfate sulfatase; Iduronate 2-sulfatase; iduronate 2-sulfatase 14 kDa chain; iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; Idursulfase; unnamed protein product

          View more View less

          Gene Aliases: AW214631; ID2S; IDS; MPS2; SIDS

          View more View less

          UniProt ID: (Human) P22304, (Mouse) Q32KI7

          View more View less

          Entrez Gene ID: (Human) 3423, (Mouse) 15931, (Rat) 363513

          View more View less

          Function(s)
          iduronate-2-sulfatase activity calcium ion binding protein binding sulfuric ester hydrolase activity hydrolase activity metal ion binding catalytic activity molecular_function
          Process(es)
          metabolic process glycosaminoglycan catabolic process heparan sulfate proteoglycan catabolic process dermatan sulfate catabolic process carbohydrate derivative catabolic process biological_process
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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