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Fabgennix
IFI27 Polyclonal Antibody
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Product Details
IFI27-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 1-50 on human Interferon alpha-inducible protein 27, mitochondrial isoform 2.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310061N23Rik; Interferon alpha-induced 11.5 kDa protein; Interferon alpha-inducible protein 27, mitochondrial; Interferon-stimulated gene 12a protein; ISG12; ISG12(a); p27; unnamed protein product
Gene Aliases: FAM14D; IFI27; ISG12; ISG12A; P27
UniProt ID: (Human) P40305
Entrez Gene ID: (Human) 3429
negative regulation of transcription from RNA polymerase II promoter
immune system process
apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
modulation by host of viral genome replication
innate immune response
regulation of protein export from nucleus
defense response to virus
type I interferon signaling pathway
pyroptosis
protein K48-linked ubiquitination
extrinsic apoptotic signaling pathway
intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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