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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • IFIT2 Antibodies

          Invitrogen

          IFIT2 Polyclonal Antibody

          View all (4) IFIT2 antibodies

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          Cite IFIT2 Polyclonal Antibody

          • Antibody Testing Data (1)
          IFIT2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          IFIT2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          IFIT2 Antibody (PA5-89415) in WB

          Western blot analysis of IFIT2 in extracts of various cell lines. Samples were incubated with IFIT2 Polyclonal antibody (Product # PA5-89415) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          IFIT2 Antibody in Western Blot (WB)
          IFIT2 Polyclonal Antibody

          Product Details

          PA5-89415

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 273-472 of human IFIT2 (NP_0015384)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.82 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2805557

          Product Specific Information

          Immunogen sequence: ALEYIPNNAY LHCQIGCCYR AKVFQVMNLR ENGMYGKRKL LELIGHAVAH LKKADEANDN LFRVCSILAS LHALADQYED AEYYFQKEFS KELTPVAKQL LHLRYGNFQL YQMKCEDKAI HHFIEGVKIN QKSREKEKMK DKLQKIAKMR LSKNGADSEA LHVLAFLQEL NEKMQQADED SERGLESGSL IPSASSWNGE; Positive Samples: A-431, HepG2; Cellular Location: Cytoplasm, Endoplasmic reticulum

          Target Information

          IFIT2 belongs to the IFIT family. It contains 6 TPR repeats. IFIT genes comprise a large family with three (Ifit1, Ifit2, and Ifit3) and four (IFIT1, IFIT2, IFIT3, and IFIT5) members in mice and humans, respectively. IFITproteins are produced in human body that are supposed to confer immunity against viral infection. These proteins are generally produced during viral infection, Interferon (IFN) treatment, and during pathogen recognition (Pathogen associated molecular pattern recognition) byimmune systemduring infections.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: IFI-54K; IFIT-2; Interferon, alpha-inducible protein (MW 54kD); Interferon-induced 54 kDa protein; interferon-induced protein 54; Interferon-induced protein with tetratricopeptide repeats 2; ISG-54 K

          View more View less

          Gene Aliases: CIG-42; cig42; G10P2; GARG-39; IFI-54; IFI-54K; IFI54; IFIT-2; IFIT2; ISG-54 K; ISG-54K; ISG54; P54

          View more View less

          UniProt ID: (Human) P09913

          View more View less

          Entrez Gene ID: (Human) 3433

          View more View less

          Function(s)
          RNA binding protein binding poly(A) RNA binding
          Process(es)
          apoptotic mitochondrial changes response to virus negative regulation of protein binding cellular response to interferon-alpha positive regulation of apoptotic process defense response to virus type I interferon signaling pathway
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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