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This gene is a member of the insulin-like growth factor binding protein family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
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Protein Aliases: IBP-4; IGF-binding protein 4; IGFBP; IGFBP-4; Insulin like growth factor binding protein; insulin-like growth factor binding protein 4; Insulin-like growth factor-binding protein 4
Gene Aliases: BP-4; HT29-IGFBP; IBP4; IGF-BP4; IGFBP-4; IGFBP4
UniProt ID: (Human) P22692, (Rat) P21744
Entrez Gene ID: (Human) 3487, (Rat) 360622
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