Immunogen sequence: GCFPAGAQVR LESGARVALS AVRPGDRVLA MGEDGSPTFS DVLIFLDREP HRLRAFQVIE TQDPPRRLAL TPAHLLFTAD NHTEPAARFR ATFASHVQPG QYVLVAGVPG LQPARVAAVS THVALGAYAP LTKHGTLVVE DVVASCFAAV ADHHLAQLAF WPLRLFHSLA WGSWTPGEGV HWYPQLLYRL GRLLLEEGSF HPLGMSGAGS; Positive Samples: Human placenta, Mouse kidney, Mouse liver, Mouse ovary, Rat liver, Rat lung, Rat brain; Cellular Location: Cell membrane, Extracellular side, Lipid-anchor, extracellular space
Ihh (Indian hedgehog) is a critical and possibly direct regulator of joint development. In its absence, distribution and function of Gdf5-expressing interzone-associated cells are abnormal.
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Protein Aliases: HHG-2; IHH; Indian hedgehog homolog; Indian hedgehog protein; Indian hedgehog protein C-product; Indian hedgehog protein N-product
Gene Aliases: BDA1; HHG2; IHH