|ELISA (ELISA)||Assay Dependent|
|ELISA (ELISA)||See 1 publications below|
|Tested Species reactivity||Bovine|
|Published species reactivity||Bovine|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant IL-1 beta|
|Storage conditions||4° C|
PBOIL1BI targets IL-1 beta in ELISA applications and shows reactivity with Bovine samples.
The PBOIL1BI immunogen is recombinant IL-1 beta.
PBOIL1BI detects IL-1 beta which has a predicted molecular weight of approximately 18 kDa.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IL-1 beta; IL-1beta; Interleukin-1 beta
Gene Aliases: BOS_11619; IL1B
UniProt ID: (Bovine) P09428
Entrez Gene ID: (Bovine) 281251
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