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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rat / IgG1, kappa|
|Immunogen||Recombinant human Interleukin 10.|
|Storage buffer||PBS, pH 7.2, with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||5 ul per 1x10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-gamma, TNF-alpha, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine.
RHCIL1001 was used in immunocytochemistry to establish a microfluidic method to analyze single cell secretions
|Konry T,Dominguez-Villar M,Baecher-Allan C,Hafler DA,Yarmush ML||Biosensors & bioelectronics (26:2707)||2011|
CSIF; cytokine synthesis inhibitory factor; IL10A; MGC126450; MGC126451; T-cell growth inhibitory factor; TGIF
CSIF; GVHDS; IL-10; IL10; IL10A; TGIF