|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide corresponding to residues C(102) N Y T E A F Q T Q T R P S G G K(118) of human IL-17BR.|
|Storage buffer||PBS with 0.1mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: Hela whole cell extract, HeLa cell lysate.
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are IL-17B, IL-17C, and IL-17E. Like IL-17, IL-17B, C, and E are able to induce proinflammatory responses but don't bind to the IL-17 receptor suggesting additional IL-17R related receptors might exist. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in kidney and liver and at moderate level in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.