|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Rat / IgG2a, kappa|
|Storage buffer||PBS with sucrose, 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||5 ul per 1x10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Differential development of plasmacytoid dendritic cells in Th1- and Th2-like cytokine milieus.
RHCIL204 was used in flow cytometry to test if Th1- and Th2-like conditions alter antigen expression and function of plasmacytoid dendritic cells
|Bratke K,Klein C,Kuepper M,Lommatzsch M,Virchow JC||Allergy (66:386)||2011|
Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines.
RHCIL204 was used in flow cytometry to report an in vitro differentiation assay in which human naive CD4(+) cells are driven toward either the Th1 or Th2 phenotype and study them.
|Cousins DJ,Lee TH,Staynov DZ||Journal of immunology (Baltimore, Md. : 1950) (169:2498)||2002|
|Not Applicable||Not Cited||
Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood.
RHCIL204 was used in flow cytometry to use flow cytometry to study granzyme A, B, and K expression in human peripheral blood lymphocytes
|Bratke K,Kuepper M,Bade B,Virchow JC,Luttmann W||European journal of immunology (35:2608)||2005|